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Toxicity publication from Wenzhou China University and Oregon State University
Toxicity, uptake kinetics and behavior assessment in zebrafish embryos following exposure to perfluorooctanesulphonicacid (PFOS)

"Perfluorooctanesulphonicacid (PFOS), a persistent organic contaminant, has been widely detected in the environment, wildlife and humans, but few studies have assessed its effect on aquatic organisms. The present study evaluated the effect of PFOS on zebrafish embryos [...] " Elsevier 2010 Haihua Huang et al.
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Science Publication : Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation.
Harvard University published in Science on January the 15th, the results of its drug profiling using ViewPoint's high throughput technology.

"A major obstacle for the discovery of psychoactive drugs is the inability to predict how small molecules will alter complex behaviors. We report the development and application of a high-throughput, quantitative screen for drugs that alter the behavior of larval zebrafish. We found that the multidimensional nature of observed phenotypes enabled the hierarchical clustering of molecules according to shared behaviors. [...]"

"We can screen 112 compounds every three days, or 224 compounds per week." Science 327, 348 (2010) - Dr. Jason Rhiel et al. - Harvard Univ. Read more on the screening technology...


New Software : ZebraFish HeartBeat calculation
ZebraFish cardiac cycle is an important parameter to verify the toxicity effect of a compound or to check physiological parameters of a mutant.
The ZebraLab software enable to automate this task and various experiment involving movement of organs (such as the gut transit).
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Upcoming events
  • May 6-7th, 2010 - Methods in ZebraFish Behavior analysis 2010 - Paris, France
  • July 3-7th, 2010 - Forum of European Neuroscience Booth#126 - Amsterdam, Netherland

    • High throughput Rodent Phenotyping
    PhenoRack is an high throughput system able to monitor Home Cage Activity 24 hours a day, 7 days a week. In a few steps you start monitoring the behavior of your animals in racks.
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